Cavernous Malformations of the Nervous System

Cavernous Malformations of the Nervous System
Cambridge University Press | October 17, 2011 | ISBN-10: 0521764270 | 208 pages | PDF | 3.5 MB
Questions regarding the nature and appropriate management of cavernous
malformation (CM) have clouded researchers and those faced with making
clinical decisions for several decades. CMs may be seen as an incidental
finding on MRI studies, or they may present with symptoms, such as
seizures or intracranial hemorrhage, often causing severe neurologic
deficit. Cavernous Malformations of the Nervous System provides a
comprehensive and authoritative review of the current practice in
diagnosis and management of these cerebrovascular disorders. Emphasis
has been laid on the understanding of basic sciences with chapters
committed to understanding of CCM1, 2 and 3 genes and their role in CCM
biology, as well as clinical genetics. Controversial topics which
continue to pose treatment challenges such as safety of anticoagulation
and prophylactic management during pregnancy are also discussed. This
book will be of interest to basic science researchers, neurosurgeons and
vascular neurologists both in academic institutions and private
practice.

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