Celiac Disease: From Pathophysiology to Advanced Therapies

"Celiac Disease: From Pathophysiology to Advanced Therapies" ed. by Peter Kruzliak and Govind Bhagat
InTeOp | 2012 | ISBN: 9535106845 9789535106845 | 194 pages | PDF | 6 MB
This book covers most of the aforementioned controversial and yet
unresolved topics by including the contributions of experts in Celiac
disease (CD).What the reader will surely find stimulating about this
book is not only its exhaustive coverage of our current knowledge of CD,
but also provocative new concepts in disease pathogenesis and
treatment.

Celiac disease (CD) is an immune-mediated enteropathy triggered by the
ingestion of gluten-containing grains (including wheat, rye and barley)
in genetically susceptible individuals. CD can manifest itself with a
previously unappreciated range of clinical presentations, including the
typical malabsorption syndrome and a spectrum of symptoms potentially
affecting any organ system.
Since CD often presents in an atypical or even silent manner, many cases
remain undiagnosed and carry the risk of long-term complications,
including anemia and other hematological complications, osteoporosis,
neurological complications or cancer. The high prevalence of the disease
and its variety of clinical outcomes raise several interesting
questions.

Contents
Preface
Section 1 New Insights on Pathophysiology of Celiac Disease
1 Mucosal Expression of Claudins in Celiac Disease
2 Antioxidant Status of the Celiac Mucosa: Implications for Disease Pathogenesis
3 Heat Shock Proteins in Coeliac Disease
Section 2 Clinical Manifestations and Complications of Celiac Disease
4 Celiac Disease and Diabetes Mellitus Type 1
5 Hematologic Manifestations of Celiac Disease
6 Multiple Sclerosis and Celiac Disease
Section 3 Detection of Cereal Toxic Peptides Based on New Laboratory Methods
7 Sensitive Detection of Cereal Fractions that Are Toxic to Coeliac
Disease Patients, Using Monoclonal Antibodies to a Main Immunogenic
Gluten Peptide
Section 4 Advanced Therapies in Celiac Disease
8 Enzyme Therapy for Coeliac Disease: Is it Ready for Prime Time?
Section 5 Follow-up of Patients with Celiac Disease
9 Principles and Strategies for Monitoring Individuals with Celiac Disease
10 On Treatment Outcomes in Coeliac Disease Diagnosed in Adulthood

download:
http://adf.ly/B7cw5
or
http://adf.ly/B7cyp
or
http://adf.ly/B7d11
or
http://adf.ly/B7d43