The Toxicology of Fishes

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The Toxicology of Fishes
Autor: Richard T. Di Giulio, David E. Hinton

Unit I: General Principles
Introduction
Bioavailability of Chemical Contaminants in Aquatic Systems
Toxicokinetics in Fishes
Biotransformation in Fishes
Receptor-Mediated Mechanisms of Toxicity
Reactive Oxygen Species and Oxidative Stress

Unit II: Key Target Systems and Organismal Effects
Liver Toxicity
The Osmoregulatory System
Toxic Responses of the Fish Nervous System
The Endocrine System
The Immune System of Fish: A Target Organ of Toxicity
Chemical Carcinogenesis in Fishes
Toxicity Resistance

Unit III: Methodologies and Applications
Exposure Assessment and Modeling in the Aquatic Environment
Fish Toxicity Studies
Biomarkers
Aquatic Ecosystems for Ecotoxicological Research:
Considerations in Design Analysis for Fish
Ecological Risk Assessment

Unit IV: Case Studies
Mining Impacts on Fish in the Clark Fork River, Montana: A Field Ecotoxicology Case Study
Toxicology of Synthetic Pyrethroid Insecticides in Fish: A Case Study
Reproductive Impairment of Great Lakes Lake Trout by Dioxin-Like Chemicals
The Effects of Polycyclic Aromatic Hydrocarbons in Fish from Puget Sound, Washington
Effects of the Exxon Valdez Oil Spill on Pacific Herring in Prince William Sound, Alaska
Case Study: Pulp and Paper Mill Impacts
Estrogenic Effects of Treated Sewage Effluent on Fish: Steroids and Surfactants in English Rivers

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